NAD+ 500mg
For Research Use Only
Best Seller -20% OFF
≥98%
HPLC Verified
COA
Every Batch
USA
Jessup, PA
Longevity & Cellular / Coenzymes

NAD+ 500mg

Research Grade

The cellular energy currency coenzyme — NAD+ levels decline 50% with aging, impairing sirtuins, DNA repair, and mitochondrial function. Research-grade 500mg for NAD+ restoration protocols.

≥98% Purity COA Included Cold Pack Shipping Same-Day Ship
$118.00 $148.00 Save 20%
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4.8 · 8 reviews
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$106.20
$118.00
Purity
≥98%
Weight
500mg
CAS
53-84-9
Formula
C21H27N7O14P2
Form
5 mL Multi-Dose Vial
Vial
5 mL Multi-Dose Vial

Product Overview

NAD+ (Nicotinamide Adenine Dinucleotide) is a fundamental coenzyme found in all living cells, serving as the central hydride transfer agent in over 500 enzymatic reactions. It functions as both a redox cofactor (interconverting between NAD+ and NADH) and as a substrate for critical signaling enzymes including sirtuins (SIRT1–7), PARP1/2 (DNA repair enzymes), and cyclic ADP-ribose synthases (CD38, CD157). NAD+ levels decline by 50% or more between age 20 and 60 in most tissues — a decline now mechanistically linked to the hallmarks of aging including mitochondrial dysfunction, genomic instability, epigenetic dysregulation, and stem cell exhaustion. The 500mg format in a 5mL multi-dose vial supports intravenous or subcutaneous research protocols.

Methodology Note: This product summary references published preclinical and clinical research. 22EXO does not make therapeutic claims. All compounds are sold strictly for laboratory and research applications.

Disclaimer: This product is sold for research and laboratory use only. Not for human consumption. By purchasing, you agree to our terms of service and confirm that this product will only be used for legitimate research purposes.

Customer Reviews

4.8 · 8 reviews
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good but reconstitution takes time at 500mg
by Sara K. · 2026-05-08 · ✓ Verified
★★★★☆

dissolves fully but takes a couple minutes of gentle inversion. quality is there. just plan ahead

500mg vials are huge
by Gabe · 2026-05-01 · ✓ Verified
★★★★★

the 500mg vial is much bigger than i expected. value per mg is really good vs other suppliers. nad+ in this volume is rare.

good but reconstituting 500mg takes a bit
by RM · 2026-05-01 · ✓ Verified
★★★★☆

the volume is so large it takes a couple minutes to fully dissolve. small thing. quality is there.

Generous 500mg format
by Dr. S. Gupta · 2026-05-01 · ✓ Verified
★★★★★

Outstanding purity, competitive price.

Stable and consistent
by K. Larsen · 2026-05-01 · ✓ Verified
★★★★★

Used across three rounds of cellular respiration assays. Stability has been good — stored at 2-8C after reconstitution and saw no degradation over the 30 day window per the supplier guidance.

Resources

For research use only. Not for human consumption. Not approved by the FDA for any therapeutic indication. By purchasing, you confirm that this material will be used solely for in-vitro research purposes by qualified researchers.