IGF-1 LR3 0.1mg
For Research Use Only
Premium -20% OFF
≥98%
HPLC Verified
COA
Every Batch
USA
Jessup, PA
Growth Hormone / IGF Variants

IGF-1 LR3 0.1mg

Research Grade

The most potent IGF-1 analogue — 13-fold IGFBP resistance extends half-life to 20–30 hours, providing sustained muscle satellite cell activation and PI3K/Akt/mTOR anabolic signaling.

≥98% Purity COA Included Cold Pack Shipping Same-Day Ship
$52.00 $65.00 Save 20%
You save $13.00 on this order
5 · 2 reviews
1

Free shipping on orders over $200 · Discreet packaging

Volume Pricing Discount applied automatically
$52.00
Standard
$49.40
Save 5%
$46.80
Save 10%
$44.20
Save 15%
$41.60
Save 20%
10+×
$39.00
Save 25%
Subscribe & Save 10%

Auto-ship to your lab. Pause or cancel anytime.

$46.80
$52.00
Purity
≥98%
Weight
0.1mg
CAS
946870-92-4
Formula
C400H625N111O115S9
Form
Sterile Lyophilized Powder
Vial
3 mL Multi-Dose Vial

Product Overview

IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic, recombinant analogue of human IGF-1 with two modifications: an arginine (R) substitution at position 3 replacing glutamic acid (E3R), and an additional 13-amino-acid N-terminal extension derived from a truncated variant. These modifications result in a 13-fold reduction in binding affinity for IGF binding proteins (IGFBPs), dramatically extending the half-life from approximately 12–15 hours (native IGF-1) to over 20–30 hours. IGF-1 LR3 is one of the most potent anabolic growth factors in research, mediating much of the anabolic and anti-catabolic signaling downstream of GH secretion. The 0.1mg format reflects its extraordinary potency — IGF-1 LR3 is active at nanomolar concentrations.

Methodology Note: This product summary references published preclinical and clinical research. 22EXO does not make therapeutic claims. All compounds are sold strictly for laboratory and research applications.

Disclaimer: This product is sold for research and laboratory use only. Not for human consumption. By purchasing, you agree to our terms of service and confirm that this product will only be used for legitimate research purposes.

Customer Reviews

5 · 2 reviews
Write a Review Verified customers only

Reviews are visible after we verify the email matches a recent order.

LR3 stability is the key and theirs holds up
by M.G. · 2026-05-01 · ✓ Verified
★★★★★

the long arg-3 variant should resist serum protease cleavage and 22EXO's product has performed correctly in our cell-culture experiments. consistent activity.

good
by anonymous · 2026-05-01 · ✓ Verified
★★★★★

no issues, fast shipping, COA matched

Resources

For research use only. Not for human consumption. Not approved by the FDA for any therapeutic indication. By purchasing, you confirm that this material will be used solely for in-vitro research purposes by qualified researchers.